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Effects of perindopril and valsartan on expression of transforming growth factor-β-Smads in experimental hepatic fibrosis in rats

✍ Scribed by Wei Xu; Shiling Song; Yanqing Huang; Zuojiong Gong


Book ID
108950812
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
353 KB
Volume
21
Category
Article
ISSN
0815-9319

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Connective tissue growth factor (CTGF) stimulates in vitro fibroblast proliferation and extracellular matrix synthesis. The aim of this study was to assess the role of CTGF in liver fibrogenesis. CTGF expression was investigated both at the protein and mRNA level in biopsies of chronic liver disease