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Effects of pentobarbitone on acetylcholine-activated channels in mammalian muscle

✍ Scribed by Peter W. Gage; David McKinnon

Book ID
117958264
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
761 KB
Volume
85
Category
Article
ISSN
0007-1188

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The use of cholinesterase (CHE) inhibitors provided valuable information about the mechanism(s) of neuromuscular transmission, but questions on side effects at the level of ACh-activated channels were raised. Patch-clamp recording was used to study the effects of prostigmine (PST) and methanesulfony