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Effects of pectenotoxin-1 on liver cells in vitro

✍ Scribed by Zhen-Hua Zhou; Masatoshi Komiyama; Kiyoshi Terao; Dr. Yutaka Shimada

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
476 KB
Volume
2
Category
Article
ISSN
1056-9014

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✦ Synopsis

Abstract

The effects of pectenotoxin‐I (PTX~1~), a nondiarrheagenic toxin from mussels, on liver cells were investigated by fluorescence microscopy. The in vitro application of PTX~1~, to these cells induced reduction in number and loss in radial arrangement of microtubules. It also induced disruption of stress fibers and accumulation of actin at the cellular peripheries. Further studies are worthwhile to explore the feasibility of using PTX~1~, as a tool for analyzing the properties of cytoskeletal proteins. Β© wiley‐Liss, Inc.

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