Effects of P2, a peptide derived from a homophilic binding site in the neural cell adhesion molecule on learning and memory in rats
โ Scribed by L. Rizhova; B. Klementiev; K. Cambon; C. Venero; C. Sandi; E. Vershinina; E. Vaudano; V. Berezin; E. Bock
- Book ID
- 116788279
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 801 KB
- Volume
- 149
- Category
- Article
- ISSN
- 0306-4522
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## Abstract The neural cell adhesion molecule (NCAM) plays a pivotal role in neural development, regeneration, and plasticity. NCAM mediates adhesion and subsequent signal transduction through NCAMโNCAM binding. Recently, a peptide ligand termed P2 corresponding to a 12โaminoโacid sequence in the F
## Abstract The neural cell adhesion molecule (NCAM) plays a key role in neural development, regeneration, and synaptic plasticity. The crystal structure of a fragment of NCAM comprising the three Nโterminal immunoglobulin (Ig)โlike modules indicates that the first and second Ig modules bind to eac