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Effects of p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt on leukemic infiltration of brain and liver in mice bearing P388 leukemia

โœ Scribed by Sava, Gianni; Giraldi, Tullio; Bartoli-Klugmann, Fiora; Decorti, Giuliana; Mallardi, Franco

Book ID
122801820
Publisher
Elsevier Science
Year
1984
Weight
262 KB
Volume
20
Category
Article
ISSN
0277-5379

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Comparison of the antitumor activity of
Comparison of the antitumor activity of DTIC and 1-p-(3,3-dimethyl-1-triazeno) benzoic acid potassium salt on murine transplantable tumors and their hematological toxicity
โœ Tina Colombo; Maurizio D'Incalci ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer ๐ŸŒ English โš– 270 KB

This study describes a comparison of 1-p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (DM-COOK) and imidazole-4-carboxamide,5-(3,3-dimethyl-1-triazeno) (DTIC) with reference to antitumor activity on different murine tumors and hematological toxicity. DM-COOK appeared comparably or slightly m