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Effects of osteoblast-like cells on bone-related and invasive gene expressions in breast cancer cells

โœ Scribed by Hichame IdBoufker; Laurence Lagneaux; Tatiana Tondreau; Hugues Duvillier; Jean-Jacques Body; Fabrice Journe


Book ID
116320548
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
59 KB
Volume
42
Category
Article
ISSN
8756-3282

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โœ Kazuo Ohishi; Naoya Fujita; Yoshihiro Morinaga; Takashi Tsuruo ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer ๐ŸŒ English โš– 826 KB

Bone is one of the most common sites of metastasis in breast cancer. For metastasis to occur in bone, tumor cells must induce osteolysis by osteoclasts. Degradation of the osteoid layer by type I collagenase is a necessary process before osteolysis can occur because the osteoid layer hinders osteocl