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EFFECTS OF ORAL RETINOID (VITAMIN A AND ETRETINATE) THERAPY ON PHOTOCARCINOGENESIS IN HAIRLESS MICE

โœ Scribed by Graham E. Kelly; William D.Meikle; A. G. Ross Sheil

Book ID
114895596
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
288 KB
Volume
50
Category
Article
ISSN
0031-8655

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Hyperkeratotic skin changes in hairless mice can be induced by oral administration of 20,25-diazacholesterol (DZC), a hypocholesterolemic agent. This system has been reported as an animal model of ichthyosis [3] and used for the investigation of the effects of topical retinoids [2]. The aim of our p