The effects of oral liarozole on epiderm
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Kuijpers; Van Pelt; Bergers; Boegheim; Den Bakker; Siegenthaler; Van DE Kerkhof;
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Article
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1998
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John Wiley and Sons
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English
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The imidazole derivative liarozole is a potent inhibitor of cytochrome P450-dependent 4-hydroxylation of endogenous all-trans retinoic acid, thereby increasing the levels of all-trans retinoic acid in both plasma and skin. As part of a large, double-blind, randomized clinical study, we investigated