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Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers

โœ Scribed by Bhagwant D Rege; Joseph P.Y Kao; James E Polli

Book ID
114302016
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
179 KB
Volume
16
Category
Article
ISSN
0928-0987

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Poly(ethylene glycol) (PEG) is an excipient commonly used in pharmaceutical formulations to increase the aqueous solubility of drugs intended for oral administration. High concentrations of PEG are often used to solubilize drug candidates for in vitro experiments in cell culture (e.g., Caco-2 cell p