Effects of nitrendipine, dotarizine and diltiazem on intracellular calcium in cultured bovine aortic endothelial cells
โ Scribed by A. Salameh; A. Eisert; G. Schomecker; S. Dhein; U. Fricke; W. Klaus
- Book ID
- 119180197
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 137 KB
- Volume
- 31
- Category
- Article
- ISSN
- 1043-6618
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We studied the ionic currents activated by basic fibroblast growth factor (bFGF) and insulin-like growth factor-I (IGF-I) in cultured bovine aortic endothelial cells (BAE-1) by using patch-clamp and single-cell fluorimetric calcium measurements. In whole-cell, voltage-clamp experiments at V h ฯญ ฯช50
## Abstract Endothelial cells (EC) line the heart and blood vessels, and they are the principal cellular components of the microvasculature. The presence of circulating platelets is believed to be necessary to maintain the integrity of the capillary endothelium. Growing EC in culture provides an op