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Effects of nimesulide on nitric oxide-induced hyperalgesia in humans—a neurophysiological study

✍ Scribed by Giorgio Sandrini; Cristina Tassorelli; Alberto Proietti Cecchini; Enrico Alfonsi; Giuseppe Nappi


Book ID
114015006
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
94 KB
Volume
450
Category
Article
ISSN
0014-2999

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Effects of nimesulide on kainate-induced
✍ Eduardo Candelario-Jalil; Olga Sonia León 📂 Article 📅 2003 🏛 BioMed Central 🌐 English ⚖ 646 KB

## Background: The cyclooxygenase-2 inhibitor nimesulide is able to reduce kainate-induced oxidative stress in vivo. here we investigate if this effect is mediated by the direct antioxidant properties of nimesulide using a well-characterized in vitro model of kainate toxicity. ## Results: Exposur