𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effects of nicotine on cytochrome P450 2A6 and 2E1 activities

✍ Scribed by Janne Hukkanen; Peyton Jacob III; Margaret Peng; Delia Dempsey; Neal L. Benowitz


Book ID
108642434
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
600 KB
Volume
69
Category
Article
ISSN
0306-5251

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Effect of nicotine on cytochrome P450 1A
✍ Janne Hukkanen; Peyton Jacob III; Margaret Peng; Delia Dempsey; Neal L. Benowitz πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 490 KB
Effects of cytochrome P450 (CYP) 2A6 gen
✍ Hiromasa Tsukino; Yoshiki Kuroda; Delai Qiu; Hiroyuki Nakao; Hirohisa Imai; Taka πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 67 KB

## Abstract Cytochrome P450 (CYP) 2A6 and __CYP2E1__ are enzymes with a high ability to activate a nitrosamine, 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK), to its potent and ultimate carcinogens. The polymorphic __CYP2A6__ and __CYP2E1__ have been implicated in increased susceptibility to

Inhibitory effects of antiparasitic drug
✍ J. A. Hasler; I. Johansson; C. M. Masimirembwa πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 409 KB

The interaction of antiparasitic drugs with the polymorphic cytochrome P450 2D6 was studied in human liver microsomes. Of ten different drugs tested, three quinolines, oxamniquine, primaquine and chloroquine inhibited microsomal CYP2D6-catalysed formation of l'hydroxybufuralol at concentrations tha