The purpose of this study was to investigate micrometastasis (MM) and tumor cell microinvolvement (TCM) in the regional lymph nodes of patients with esophageal squamous cell carcinoma (SCC). ## METHODS. MM was defined as individual tumor cells or tumor cell clusters Ο½0.5 mm in greatest dimension
Effects of neoadjuvant chemotherapy on primary tumor and lymph node metastasis in esophageal squamous cell carcinoma: additive association with prognosis
β Scribed by Hirofumi Akita; Yuichiro Doki; Masahiko Yano; Hiroshi Miyata; Isao Miyashiro; Hiroaki Ohigashi; Osamu Ishikawa; Akiko Nishiyama; Shingi Imaoka
- Book ID
- 108982135
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 195 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1120-8694
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## Background: Recent studies on the role of bcl-2 in malignant tumors have suggested its prognostic significance. the goals of the current study were to determine any correlation between bcl-2 expression in esophageal squamous cell carcinoma and histopathology, lymph node metastasis, and clinical
## BACKGROUND. Esophageal squamous cell carcinoma (ESCC) is associated with poor prognosis and lymph node metastasis is one of the critical prognostic factors. Although it is important to elucidate the genetic aberrations underlying its lymph node metastasis, to the authors' knowledge little is kn