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Effects of naturally occurring antioxidants on combined 1,2-dimethylhydrazine- and 1-methyl-1-nitrosourea-initiated carcinogenesis in F344 male rats

✍ Scribed by Imaida, K.; Hirose, M.; Yamaguchi, S.; Takahashi, S.; Ito, N.


Book ID
123087926
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
606 KB
Volume
55
Category
Article
ISSN
0304-3835

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## Abstract Combined effects of sodium nitrite (NaNO~2~) and 2‐amino‐3‐methylimidazo[4,5‐__f__]quinoline (IQ) on liver, colon and Zymbal's gland carcinogenesis were assessed using a rat two‐stage carcinogenesis model, with a focus on involvement of oxidative stress. Male 6‐week‐old F344 rats were g