Perturbation of EGF-activated MEK1 and P
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Shaochun Yan; Shelly Krebs; Kirk J. Leister; Charles E. Wenner
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Article
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2000
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John Wiley and Sons
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English
⚖ 302 KB
👁 1 views
In mouse C3H 10T1/2 cells, we previously reported that TGF-beta1 first delays and later potentiates EGF-induced DNA synthesis corresponding to an inhibition of EGF-induced cyclin D1 expression at t = 13 h. We report here that in accord with DNA synthesis kinetics, TGF-beta1 initially suppresses EGF-