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Effects of Na+H+ exchange inhibition on cardiac reperfusion arrhythmias

✍ Scribed by S.C. Dennis; W.A. Coetzee; E. Cragoe Jr; L.H. Opie


Book ID
118916623
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
120 KB
Volume
20
Category
Article
ISSN
0022-2828

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Antiarrhythmic effects of Na-H exchange
✍ Morris Karmazyn πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 97 KB

## Abstract The sodium–hydrogen exchange (NHE), which extrudes protons for concomitant sodium influx, represents the primary mechanism by which the cardiac cell regulates its pH, particularly under excessive proton production. Despite this critical role, NHE, which is activated during both ischemia