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Effects of N-Acetylcysteine in hepatic ischemia-reperfusion injury during hemorrhagic shock

✍ Scribed by A.O.V Portella; E.F.S Montero; L.F Poli de Figueiredo; A.S Bueno; A.A Thurow; F.G Rodrigues


Book ID
116929791
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
95 KB
Volume
36
Category
Article
ISSN
0041-1345

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We investigated whether intraportal injection of 150 mgkg N-acetylcysteine (NAC) into rats reduced hepatic ischemia-reperfusion injury after 48 hours of cold storage and 2 hours of reperfusion. The organ was isolated and perfused to evaluate liver function. The control group received an intraportal