𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effects of mutations on herpes simplex virus 1 thymidine kinase functionality: An in vitro assay based on detection of monophosphate forms of acyclovir and thymidine using HPLC/DAD

✍ Scribed by Nicolas Malartre; Roselyne Boulieu; Nisrine Falah; Jean-Claude Cortay; Bruno Lina; Florence Morfin; Emilie Frobert

Book ID
119190597
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
386 KB
Volume
95
Category
Article
ISSN
0166-3542

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

An optimized thymidylate kinase assay, b
An optimized thymidylate kinase assay, based on enzymatically synthesized 5-[125I]iododeoxyuridine monophosphate and its application to an immunological study of herpes simplex virus thymidine-thymidylate kinases
✍ Anders R. Karlström; J.Simon Gronowitz 📂 Article 📅 1987 🏛 Elsevier Science 🌐 English ⚖ 1020 KB

The biological synthesis and purification of 5-[125I]iododeoxyuridine monophosphate (IdUMP) are described. The specificity of IdUMP as substrate in the thymidylate monophosphate kinase (TMPK) assay is demonstrated, and a 100-fold gain in sensitivity as compared to the conventional TMPK assay is show