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Effects of monomethylfumarate on dendritic cell differentiation

✍ Scribed by N.H.R. Litjens; M. Rademaker; B. Ravensbergen; H.B. Thio; J.T. van Dissel; P.H. Nibbering


Book ID
108668563
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
308 KB
Volume
154
Category
Article
ISSN
0007-0963

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Monomethylfumarate affects polarization
✍ Nicolle H. R. Litjens; Mirjam Rademaker; Bep Ravensbergen; Delphine Rea; Mariena πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 235 KB

Psoriasis vulgaris, a type-1 cytokine-mediated chronic skin disease, can be treated successfully with fumaric acid esters (FAE). Beneficial effects of this medication coincided with decreased production of IFN-gamma. Since dendritic cells (DC) regulate the differentiation of T helper (Th) cells, thi