Effects of monocyte-macrophage colony-stimulating factor (M-CSF) on in vitro erythropoiesis of marrow progenitor cells from patients with renal anemia
β Scribed by Yoshifumi Kawano; Yoichi Takaue; Jun Minakuchi; Shuh Kawashima; Fumihiko Kimura; Kazuo Motoyoshi; Takanori Abe; Junko Sato; Atsushi Hirao; Shin-ichi Saito; Takeshi Suzue; Yasuhiro Kuroda
- Book ID
- 114791895
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 577 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0902-4441
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## Abstract Addition of lipopolysaccharide (LPS) to the culture of mouse myeloid stem cells (CFU~c~) increased the incidence of compact colonies and decreased that of dispersed ones in the presence of colonyβstimulating factor (CSFβ1) which had not such an effect by itself even in high concentratio
The hematopoietic system in patients with aplastic anemia (AA) shows both quantitative and qualitative deficiencies, i.e., reduced numbers of hematopoietic progenitor cells (HPC) and impaired HPC proliferation in long-term marrow cultures (LTMC). Since recombinant human granulocyte macrophage-colony