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Effects of monoclonal antibodies to the a and β chains of the human lymphocyte function-associated (H-LFA-1) antigen on T lymphocyte functions

✍ Scribed by David W. Dongworth; Frances M. Gotch; James E. K. Hildreth; Alan Morris; Andrew J. McMichael


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
554 KB
Volume
15
Category
Article
ISSN
0014-2980

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The functional role of the LFA-1 molecule in the interaction between helper T lymphocytes and B lymphocytes was investigated using lymphocytes from patients with leukocyte adhesion deficiency, an inherited immunodeficiency characterized by a defective leukocyte expression of the LFA-1, Mac-1 (CR3) a