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Effects of monoamine oxidase inhibition by selegiline on concentrations of noradrenaline and monoamine metabolites in CSF of patients with Alzheimer's disease

✍ Scribed by E. H. Heinonen; M. Savijärvi; M. Kotila; A. Hajba; M. Scheinin

Publisher
Springer
Year
1993
Tongue
English
Weight
685 KB
Volume
5
Category
Article
ISSN
1435-1463

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## Abstract A dose‐ranging study of selegiline was performed in patients with Parkinson's disease to determine the minimal dosage of the drug able to inhibit ≥95% of platelet monoamine oxidase (MAO) activity. Different doses of selegiline (5 or 10 mg daily, 10 or 20 mg weekly) were studied in four