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Effects of mitoxantrone on action potential and membrane currents in isolated cardiac myocytes

โœ Scribed by Ge-Xin Wang; Xiao-Bo Zhou; Thomas Eschenhagen; Michael Korth

Book ID
110004295
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
208 KB
Volume
127
Category
Article
ISSN
0007-1188

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Effects of calcitonin gene-related pepti
Effects of calcitonin gene-related peptide on membrane currents in mammalian cardiac myocytes
โœ Toshiaki Nakajima; Reiko Takikawa; Tsuneaki Sugimoto; Yoshihisa Kurachi ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 687 KB

We examined the effects of calcitonin gene-related peptide (CGRP) on the membrane currents of single atrial and ventricular cells of guinea pig heart. The tightseal whole-cell voltage-clamp technique was used. In atrial cells, like isoproterenol, CGRP increased the L-type Ca channel current (ICa.L)