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EFFECTS OF MINERALOCORTICOIDS ON RNA AND PROTEIN SYNTHESIS IN MDCK CELLS

โœ Scribed by Chia-Ping H. Yang; Melanie H. Cobb; Douglas M. Jefferson; Walter N. Scott

Book ID
118718925
Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
147 KB
Volume
372
Category
Article
ISSN
0890-6564

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The antitumor agent hadacidin (N-formyl-hydroxyamino-acetic acid), at 4 mM, inhibited the multiplication of clone 4 Madin Darby canine kidney (MDCK) cells within 24 hr. Growth resumed rapidly upon replacement of hadacidin with aspartate, an observation consistent with the drug's action as a competit