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Effects of MIF-1 and three related peptides on reserpine-induced hypothermia in mice

✍ Scribed by Abba J. Kastin; Lynda C. Honour; David H. Coy


Book ID
113218528
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
276 KB
Volume
15
Category
Article
ISSN
0091-3057

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## Abstract A series of new catechol ether imidazolidinones incorporating structural features of rolipram and Ro 20‐1724 were synthesized as inhibitors of the calcium‐independent phosphodiesterase (IPDE) from rat cerebral cortex. Several compounds were found to be more potent than rolipram as IPDE