Effects of Melatonin on the Proliferation and cis-Diamminedichloroplatinum (CDDP) Sensitivity of Cultured Human Ovarian Cancer Cells
β Scribed by Masayuki Futagami; Shigemi Sato; Tomomi Sakamoto; Yoshihito Yokoyama; Yoshiharu Saito
- Book ID
- 112248621
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 93 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0090-8258
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The results presented here demonstrate that a cisdiamminedichloroplatinum(II) (DDP)-resistant human ovarian-carcinoma cell line is also cross-resistant to the spermine analogue N 1 ,N 12 -bis(ethyl)spermine (BESPM). We report that C13\* cells, which are approximately 20-fold resistant to DDP, simila
The ability of 12-0-tetradecanoylphorbol-I 3-acetate (TPA) and D,L-buthionine-S,R-sulphoximine (BSO) to modulate cisdiamminedichloroplatinum(ll) (CDDP) sensitivity was investigated in human ovarian cancer cell lines sensitive (KF) or with intrinsic resistance (KK and MH) to CDDP. The KK and MH cell