The effect of melatonin on inhibition of cell growth was studied in CT-26, a murine colon carcinoma-derived cell line. Cells growing in exponential phase were exposed to low (10(-7)-10(-10) M) and high doses (1, 2 and 3 x 10(-3) M) of melatonin during 24 h. Synthesis of DNA was measured by 5-bromo-2
β¦ LIBER β¦
Effects of melatonin on proliferation of cancer cell lines
β Scribed by Konstantinos T. Papazisis; Demetrios Kouretas; George D. Geromichalos; Efthimios Sivridis; Olga K. Tsekreli; Konstantinos A. Dimitriadis; Alexander H. Kortsaris
- Book ID
- 111264032
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 694 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0742-3098
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## Background: Management of prostate cancer that has spread outside of the prostate capsule is a difficult problem. innovative, non-toxic approaches to the disease are required. new, relatively non-toxic vitamin d3 analogs have recently been synthesized. we report that several of these compounds h