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Effects of mechanistically distinct NF-κB inhibitors on glial inducible nitric-oxide synthase expression

✍ Scribed by Randall L. Davis; Alma C. Sanchez; Daniel J. Lindley; Simon C. Williams; Peter J. Syapin


Book ID
116789948
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
395 KB
Volume
12
Category
Article
ISSN
1089-8603

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## Abstract Expression of inducible nitric oxide synthase (iNOS), which leads to the production of nitric oxide (NO), is stimulated by proinflammatory cytokines such as interleukin‐1β (IL‐1β) and tumor necrosis factor‐α (TNF‐α). Here we report on the roles of nuclear factor‐κB (NF‐κB) and mitogen‐a