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Effects of M16209 on insulin secretion in isolated, perfused pancreases of normal and diabetic rats

✍ Scribed by Kazuo Nakayama; Nobuya Murakami; Masahiko Ohta; Katsuaki Kato; Tatsuto Notsu; Masahiro Mizota; Ichitomo Miwa; Jun Okuda


Book ID
115890060
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
522 KB
Volume
276
Category
Article
ISSN
0014-2999

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Loss of a priming effect of glucose on A
✍ V. Grill; S. EfendiΔ‡ πŸ“‚ Article πŸ“… 1983 πŸ› Springer 🌐 English βš– 543 KB

Under normal conditions, glucose acutely influences pancreatic islet B, A and D cell secretion. In addition, prior exposure to glucose modulates the secretory responsiveness of these cells (priming effect). We have tested whether alloxan diabetes influences priming effects of glucose on A and D cell