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Effects of treatment with small interfering RNA on joint inflammation in mice with collagen-induced arthritis

✍ Raymond M. Schiffelers; Jun Xu; Gert Storm; Martin C. Woodle; Puthupparampil V. 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 107 KB 👁 2 views

## Abstract ## Objective RNA interference is a process in which genes can be silenced sequence‐specifically. In mammals, RNA interference can be invoked by introduction of small (19–21‐nucleotide) double‐stranded RNA molecules known as small interfering RNA (siRNA) into cells. Thereby, siRNA offer