Effects of low-dose ethanol on rat progeny upon inhalation exposure during gestation
β Scribed by A. V. Liopo; M. S. Omel'yanchik; O. V. Chumakova
- Publisher
- Springer US
- Year
- 1996
- Tongue
- English
- Weight
- 262 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0007-4888
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## Abstract Postnatal exposure (from the second day after birth to 30 days) of rat pups to low levels of lead acetate (50 mg/kg body weight/day), administered by gastric intubation, yielded a maximum blood level of 76.1ΞΌg/100 ml, at day 15 of age. Cerebellar and hippocampal lead contents were 8.67ΞΌ
Ethanol (1, 2 or 5 g kg-') and lead (0.55 g I-' in drinking water) were given either alone or in combination for 4 months to rats. The uptake of lead in tissues, some lead-sensitive variables, the levels of biogenic amines in different brain regions, hepatic lipid peroxidation, glycogen and blood gl