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Effects of long-term ursodeoxycholate administration on expression levels of secretory low molecular weight phospholipases A2 and mucin genes in patients with multiple cholesterol stones

✍ Scribed by Kano, M.; Shoda, J.; Ueda, T.; Iwasaki, R.; Irimura, T.; Urasaki, T.; Kawauchi, Y.; Asano, T.; Matsuzaki, Y.; Tanaka, N.


Book ID
123569387
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
177 KB
Volume
114
Category
Article
ISSN
0016-5085

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Effects of long-term ursodeoxycholate ad
✍ Masahito Kano; Junichi Shoda; Tatsuro Irimura; Tetsuya Ueda; Ryu Iwasaki; Tetsuy πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 444 KB

Group IIA phospholipase A2 (PLA2), a secretory low-molecular-weight PLA2, may play a critical role in the process of gallbladder mucosal inflammation in multiple cholesterol stones, which in turn may produce biliary pronucleating proteins as well as mucin. On the other hand, ursodeoxycholate (UDC) d