Effects of long term exposure to the mycotoxin fumonisin B1 in p53 heterozygous and p53 homozygous transgenic mice
β Scribed by Bondy, Genevieve; Mehta, Rekha; Caldwell, Don; Coady, Laurie; Armstrong, Cheryl; Savard, Marc; Miller, J. David; Chomyshyn, Emily; Bronson, Roni; Zitomer, Nicholas; Riley, Ronald T.
- Book ID
- 118253627
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 790 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0278-6915
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## Abstract Defects in apoptosis have been implicated in chemoresistance of colon cancer cells. We report here the ability to resist to 5βfluorouracilβinduced apoptosis of 8 colon cancer cell lines differing in __p53__ and __bax__ status: p53^β/0^bax^+/+^ for TC7, SW480, HTβ29; p53^+/+^bax^β/β^ for