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Effects of long-term administration of sulindac on APC mRNA and apoptosis in colons of rats treated with azoxymethane

✍ Scribed by Y. Kishimoto; K. Yashima; T. Morisawa; T. Ohishi; A. Marumoto; A. Sano; Y. Idobe-Fujii; N. Miura; G. Shiota; Y. Murawaki; J. Hasegawa


Book ID
106123208
Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
288 KB
Volume
128
Category
Article
ISSN
1432-1335

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Functional, biochemical and histological parameters of hepatotoxicity were assessed in male Sprague-Dawley rats receiving amiodarone (Am) short-term by gavage (5, 50, 150 and 500 mg Am kg-' day-', 10 days) or dietary exposure (50 ppm, 1500 ppm, 4-week duration), or by long-term dietary exposure (50