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Effects of ketoconazole on the polymorphic 4-hydroxylations of S- mephenytoin and debrisoquine.

✍ Scribed by JO Atiba; TF Blaschke; GR Wilkinson


Book ID
117944872
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
729 KB
Volume
28
Category
Article
ISSN
0306-5251

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Hydroxylation polymorphisms of debrisoqu
✍ G. AlvΓ‘n; P. Bechtel; L. Iselius; U. Gundert-Remy πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 454 KB

European data on the polymorphic metabolism of debrisoquine, sparteine, dextromethorphan and mephenytoin have been collected. No significant difference in phenotype frequencies was found between the separate series for debrisoquine, sparteine and dextromethorphan, which supports the claim that these