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Effects of K+channel blockers on inwardly and outwardly rectifying whole-cell K+currents in sheep parotid secretory cells

โœ Scribed by T. Ishikawa; D. I. Cook

Publisher
Springer
Year
1993
Tongue
English
Weight
974 KB
Volume
133
Category
Article
ISSN
0022-2631

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The ACh-induced whole-cell currents in sheep parotid secretory cells. Do BK channels really carry the ACh-evoked whole-cell K+current?
โœ T. Hayashi; C. Hirono; J. A. Young; D. I. Cook ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer ๐ŸŒ English โš– 761 KB

As in other salivary glands, the secretory cells of the sheep parotid have a resting K+ conductance that is dominated by BK channels, which are activated by acetylcholine (ACh) and are blocked by tetraethylammonium (TEA). Nevertheless, perfusion studies indicate that TEA does not inhibit ACh-evoked