Effects of Kainic Acid in Rat Brain Synaptosomes: The Involvement of Calcium
✍ Scribed by Anna Pastuszko; David F. Wilson; M. Erecińska
- Book ID
- 111173077
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 783 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0022-3042
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📜 SIMILAR VOLUMES
N-Arylcarbamoylpyrazolines with various substituents at the para position of the carbamoyl benzene ring inhibited ATP-dependent Ca2+-uptake in synaptosomes prepared from the rat brain. The activity of these compounds was evaluated as log( 1/15,), the reciprocal logarithm of half inhibitory concentra
Seizure activity induced by kainic acid (KA) and subsequent neuronal death are thought to be associated with an increase in cytoplasmic free calcium ([Ca2+li) and can be prevented by N-methyl-D-aspartate (NMDA) antagonists. In addition to influx through receptor operated Ca2+ channels the increase i