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Effects of K074 and pralidoxime on antioxidant and acetylcholinesterase response in malathion-poisoned mice

✍ Scribed by Alessandra Antunes dos Santos; Danúbia Bonfanti dos Santos; Renata Pietsch Ribeiro; Dirleise Colle; Kaite Cristiane Peres; Júlia Hermes; Anderson Machado Barbosa; Alcir Luiz Dafré; Andreza Fabro de Bem; Kamil Kuca; Marcelo Farina

Book ID
116780276
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
693 KB
Volume
32
Category
Article
ISSN
0161-813X

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✍ Georg Petroianu; Christina Roth; Ulrike Beha; Joseph Fisher; Wolfgang Bergler; R 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 143 KB

## Abstract Intoxication with the organophosphorus compound paraoxon (POX), an inhibitor of serine hydrolases, is frequent. Although oximes are the only enzyme reactivators presently available, clinical experience with their use was rather disappointing. Recent work has shown that under certain con