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Effects of Isoprenoid Analogues of SDB-Ethylenediamine on Multidrug Resistant Tumor Cells Alone and in Combination with Chemotherapeutic Drugs

✍ Scribed by Sidorova, Tatyana A.; Nigmatov, Albert G.; Kakpakova, Eugenia S.; Stavrovskaya, Alla A.; Gerassimova, Galina K.; Shtil, Alexander A.; Serebryakov, Edward P.


Book ID
111892837
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
139 KB
Volume
45
Category
Article
ISSN
0022-2623

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## Abstract Tumor necrosis factor Ξ± (TNF) exhibits cytotoxic activity on some solid tumors and has been reported to be synergistic with topoisomerase‐II‐targeted antineoplastic agents. A wide range of TNF concentrations (from 10 to 10,000 U/ml) was tested in 9 human lung cancer cell lines (5 small‐