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Effects of isoprenaline and terbutaline on urinary excretion of histamine and its two main metabolites in systemic mastocytosis

✍ Scribed by J. J. van Doormaal; I. G. Idema; J. G. R. de Monchy; H. Breukelman; J. J. Keyzer; H. Doorenbos

Publisher
SP Birkhäuser Verlag Basel
Year
1986
Tongue
English
Weight
484 KB
Volume
18
Category
Article
ISSN
1420-908X

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The effects of cimetidine (CIM) (an inhibitor of the hepatic microsomal monooxygenase system) on the metabolism and hepatotoxicity of trichloroethylene (TRI) were studied in male Sprague-Dawley rats. Rats were given three doses of 120 mg/kg i.p. (low-dose regimen) of CIM at 0, 6 and 11 h for 1 day,