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Effects of isoflurane and ketamine on ATP-sensitive K channels in rat substantia nigra

✍ Scribed by Dai Ishiwa; Yoshinori Kamiya; Hideki Itoh; Yuriko Saito; Tateo Ohtsuka; Yoshitsugu Yamada; Tomio Andoh


Book ID
116784038
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
357 KB
Volume
46
Category
Article
ISSN
0028-3908

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✍ K. P. S. J. Murphy; S. A. Greenfield πŸ“‚ Article πŸ“… 1991 πŸ› Springer-Verlag 🌐 English βš– 460 KB

The ATP-sensitive potassium channel (KATP channel) is a unique ionophore in that it appears to reflect cell metabolism. In the brain, the highest density of binding sites for the KATP channel is the substantia nigra. To evaluate the role of the KATP channel in this key brain area for motor control,