Effects of isoarecolone, a nicotinic receptor agonist in rodent models of nicotine dependence
β Scribed by Mohammed Shoaib
- Book ID
- 105881719
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 135 KB
- Volume
- 188
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The centrally acting cholinesterase inhibitor tacrine was compared with three nicotinic acetylcholine receptor (nAChR) agonists for their abilities to enhance performance of mature adult macaques performing a computer-automated version of the delayed matching-to-sample (DMTS) task. All four drugs en
AG-4 has been characterized as a nicotinic agonist by binding (K i = 26 Β± 1.4 Β΅M) and in vitro functional assays. The antinociceptive effect of AG-4 was examined in mice and rats, using the hot plate, abdominal constriction, and paw-pressure tests. In both species, AG-4 (25-150 Β΅g per mouse icv; 100