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Effects of intense tone exposure on choline acetyltransferase activity in the hamster cochlear nucleus

✍ Scribed by Yong-Ming Jin; Donald A. Godfrey; Jie Wang; James A. Kaltenbach


Book ID
116524879
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
308 KB
Volume
216-217
Category
Article
ISSN
0378-5955

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Using microdissection and quantitative microassay, choline acetyltransferase (ChAT) activity was mapped in the cochlear nucleus (CN) and in the source nuclei of the olivocochlear bundle, the lateral superior olive and ventral nucleus of the trapezoid body. In control rats, gradients of ChAT activity

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## Abstract This study sought to determine whether maintenance of noise‐induced dorsal cochlear nucleus (DCN) hyperactivity depends on descending projections. Twenty‐two hamsters were exposed under anesthesia to a 10‐kHz tone at 125–130 dB SPL for 4 hr, and another 21 unexposed animals served as co