Effects of intense pulsed light on sun-damaged human skin, routine, and ultrastructural analysis

✍ Scribed by Victor G. Prieto; Neil S. Sadick; Josep Lloreta; Judy Nicholson; Christopher R. Shea

• Book ID: 102465756
• Publisher: John Wiley and Sons
• Year: 2002
• Tongue: English
• Weight: 279 KB
• Volume: 30
• Category: Article
• ISSN: 0196-8092
• DOI: 10.1002/lsm.10042

✦ Synopsis

Abstract

Background and Objective

New, non‐ablative methods can be used in skin rejuvenation. Histologic analysis of non‐ablative IPL effects on facial, sun‐damaged skin.

Study Design/Materials and Methods

Five female subjects, wrinkle class I or II and Fitzpatrick skin types I, II, and III. IPL treatment: once monthly, 560‐nm cut‐off filters, spot size 8×35 mm, 28–36 J/cm. Routine histology or electron microscopy on 2‐mm punches, before treatment and then 1 week, 3 months, and 12 months.

Results

Pre‐treatment specimens contained solar elastosis and perifollicular lymphoid infiltrates. Collagen and elastic fibers appeared unaffected by treatment. At 1‐week, Demodex organisms appeared coagulated.

Conclusions

Under these conditions, IPL induces minimal morphologic changes in mildly sun‐damaged skin. Some esthetic improvement may be secondary to clearing of Demodex organisms and reduction of associated lymphocytic infiltrate. Lasers Surg. Med. 30:82–85, 2002. © 2002 Wiley‐Liss, Inc.