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Effects of Insulin and Insulin-like Growth Factor-2 on the In Vitro Regeneration of the Frog Sciatic Nerve

✍ Scribed by P. A. R. EKSTRÖM; M. EDBLADH; Å. FEX-SVENNINGSEN


Book ID
119868842
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
249 KB
Volume
692
Category
Article
ISSN
0890-6564

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✍ Dr. P. A. R. Ekström; M. Edbladh; A. Edström 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 988 KB

The present study showed that insulin (0.01 pg/ml, = 2 nM) inhibited [3H]-thymidine incorporation in support cells, most likely Schwann cells, of the cultured frog sciatic nerve. A 25-35% inhibition took place in regenerating nerve preparations as well as in preparations devoid of neuronal protein s