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Effects of imatinib mesylate in patients with polycythemia vera: results of a phase II study

✍ Scribed by Kirsten Merx, Alice Fabarius, Philipp Erben, Martin Griesshammer…

Book ID
120775787
Publisher
Springer
Year
2013
Tongue
English
Weight
238 KB
Volume
92
Category
Article
ISSN
0939-5555

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Gain-of-function D816V point mutation within the kinase domain of the transmembrane receptor KIT is found in the great majority of patients with systemic mastocytosis (SM) and is attractive therapeutic target. Twenty patients with SM were enrolled during 2003-2005 in phase II clinical trial with ima