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Effects of hypoxia on protein and gene expression in fibroblast-like synoviocytes

✍ Scribed by H El-Gabalawy, K Dasuri, C Hitchon, K Wong, G Ma, M Koshiji, S Der…

Book ID
120707259
Publisher
BioMed Central
Year
2004
Tongue
English
Weight
391 KB
Volume
6
Category
Article
ISSN
1478-6354

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## Abstract ## Objective Rheumatoid synovium is characterized by hyperplasia of fibroblast‐like (type B) synoviocytes (FLS), infiltration with mononuclear leukocytes, and tissue hypoxia. Although the latter is well documented, it has received little attention in dissection of the biochemical event