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Effects of hypercapnia on the vascular resistance of the dog's hind limb

✍ Scribed by J. Litwin; A. H. Dil; D. M. Aviado


Publisher
Springer
Year
1963
Tongue
English
Weight
508 KB
Volume
277
Category
Article
ISSN
0031-6768

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✦ Synopsis


Disagreement exists concerning the effects of acute hypercapnia on the flow and vascular resistance of the cutaneo-museular area. Aceording to some authors (BE~~THAL 1930; GELLHORβ€’ and STECK 1938) hypereapnia produces in anesthetized dogs a reduetion of blood flow to the hind limbs, and there is no secondary inerease of blood flow following readmission of normal air, whieh is eharaeteristie of aeute anoxia. Aeeording to others (FLEISCH, SIBVL and PO~OMAI~EV 1932), however, both hypercapnia and anoxia elicit in cats a biphasic vasomotor response in the hind limb, the first phase being vasoconstrietor, and the second, appearing on readmission of normal air, strongly vasodilator. Unfortunately, the changes in vascular resistance were not quantitatively measured in the above experiments.


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