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Effects of Hydrostatic Pressure and Transforming Growth Factor- β 3 on Adult Human Mesenchymal Stem Cell Chondrogenesis In Vitro

✍ Scribed by Miyanishi, Keita; Trindade, Michael C.D.; Lindsey, Derek P.; Beaupré, Gary S.; Carter, Dennis R.; Goodman, Stuart B.; Schurman, David J.; Smith, R. Lane

Book ID: 121463208
Publisher: Mary Ann Liebert
Year: 2006
Tongue: English
Weight: 520 KB
Volume: 12
Category: Article
ISSN: 1076-3279
DOI: 10.1089/ten.2006.12.1419

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## Abstract Transforming growth factor‐beta (TGF‐β) mediates several and sometime opposite effects in epithelial cells, inducing growth inhibition, and apoptosis but also promoting an epithelial to mesenchymal transition (EMT) process, which enhances cell migration and invasion. TGF‐β plays relevan