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Effects of hyaluronans of different molecular weight on cartilage and synovial changes in an ovine model of osteoarthritis

โœ Scribed by Little, Christopher; Smith, Susan; Adam, Naomi; Ghosh, Peter

Book ID
109864708
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
465 KB
Volume
74
Category
Article
ISSN
0818-9641

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Effects of different molecular weight hy
Effects of different molecular weight hyaluronan products on the expression of urokinase plasminogen activator and inhibitor and gelatinases during the early stage of osteoarthritis
โœ Yih-Shou Hsieh; Shun-Fa Yang; Ko-Huang Lue; Shu-Chen Chu; Ko-Hsiu Lu ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 320 KB

## Abstract Hyaluronan or hyaluronic acid (HA) has been used to treat osteoarthritic knees for more than 30 years. Here, we tested the hypothesis that HA with high molecular weight (MW) would have greater effects than HA with low MW on the expression of the plasminogen activator (PA)/plasmin system